Publications

Below are some of Dr. Njoku’s featured publications. A comprehensive list can be found here.

Review Articles
  1. Njoku DB. Suppressive and pro-inflammatory roles for IL-4 in the pathogenesis of experimental drug-induced liver injury: a review. Expert Opin Drug Metab Toxicol. 2010 May;6(5):519-31. doi: 10.1517/17425251003601979. PMID: 20166853; PMCID: PMC3656827.
  2. Njoku DB. Drug-induced hepatotoxicity: metabolic, genetic and immunological basis. Int J Mol Sci. 2014 Apr 22;15(4):6990-7003. doi: 10.3390/ijms15046990. PMID: 24758937; PMCID: PMC4013674.
  3. Zharichenko N, Njoku DB. The Role of Pro-Inflammatory and Regulatory Signaling by IL-33 in the Brain and Liver: A Focused Systematic Review of Mouse and Human Data and Risk of Bias Assessment of the Literature. Int J Mol Sci. 2020 May 30;21(11):E3933. doi: 10.3390/ijms21113933. PMID: 32486265.
  4. Pai S, Njoku DB. The Role of Hypoxia-Induced Mitogenic Factor in Organ-Specific Inflammation in the Lung and Liver: Key Concepts and Gaps in Knowledge Regarding Molecular Mechanisms of Acute or Immune- Mediated Liver Injury. Int J Mol Sci.. 2021; 22(5):2717.
  5. Njoku DB, Schilling JD, Finck BN. Mechanisms of nonalcoholic steatohepatitis associated cardiomyopathy: key roles for liver–heart crosstalk. Curr Opin Lipidol. 2022 Oct 1;33(5):295-299. doi: 10.1097/ MOL.0000000000000845. Epub 2022 Aug 3., PMID: 35942818.
Case Reports
  1. Anderson JS, Rose NR, Martin JL, Eger EI, Njoku DB. Desflurane hepatitis associated with hapten and autoantigen-specific IgG4 antibodies. Anesth Analg. 2007 Jun;104(6):1452-3, table of contents. doi: 10.1213/01.ane.0000263275.10081.47. PMID: 17513640; PMCID: PMC3650136.
  2. Nguyen C, Rose NR, Njoku DB. Trifluoroacetylated IgG4 antibodies in a child with idiosyncratic acute liver failure after first exposure to halothane. J Pediatr Gastroenterol Nutr. 2008 Aug;47(2):199-202. doi: 10.1097/MPG.0b013e3181709fee. PMID: 18664874; PMCID: PMC2746329.
  3. Chin MW, Njoku DB, MacQuillan G, Cheng WS, Kontorinis N. Desflurane-induced acute liver failure. Med J Aust. 2008 Sep 1;189(5):293-4. PMID: 18759731.
Book Chapters, Monographs
  1. Martin JL, Njoku D. Subclavian Steal Syndrome. In: Essence of Anesthesia Practice, M. Roizen and L. Fleisher, editors. New York: W. B. Saunders Company. 298, 1997.
  2. Njoku D. Effects of Halogenated Inhalational Anesthetics on the Liver and Kidney. In: Problems in Anesthesia, M. Yaster, L. Fleisher, and D. Prough, editors. Philadelphia: Lippncott Williams & Wilkins. 10:478- 487, 1998.
  3. Martin JL, Njoku D. Subclavian Steal Syndrome. In: Essence of Anesthesia Practice, M. Roizen and L. Fleisher, editors. New York: W. B. Saunders Company. 309, 2002.
  4. Vax R and Njoku D. Branchial Cleft Cyst. In: Anesthesia for Strategies in Pediatric Anesthesia for the Palm Pilot. Ed.: RS Litman. Pocketmedicine.com, New York, NY, 2002.
  5. Kaufman S and Njoku D. Craniotomy for CNS Tumor Excision. In: Anesthesia for Strategies in Pediatric Anesthesia for the Palm Pilot. Ed.: RS Litman. Pocketmedicine.com, New York, NY, 2002.
  6. Martin J and Njoku DB. Understanding the Metabolism and Toxicity of Modern Fluorinated Anesthetics. In Anesthesiology, R. Miller editor. 5th Edition, 2004.
  7. Brady KM, Njoku DB. Latex Allergy. Decision Making in Anesthesiology, 4th edition. Mosby Year Book, 2007.
  8. Sharma R.B., Burek C.L., Cihákova D., Njoku D.B., Rose N.R. (2007) Environmental Factors in Autoimmune Endocrinopathies. In: Weetman A.P. (eds) Autoimmune Diseases in Endocrinology. Contemporary Endocrinology. Humana Press, 2007.
  9. Njoku D. Branchial Cleft Cyst. In: Anesthesia for Strategies in Pediatric Anesthesia for the Palm Pilot. Second Edition. Ed. RS Litman. Pocketmedicine.com, New York, NY, 2007.
  10. Kaufman S and Njoku D. Craniotomy for CNS Tumor Excision. In: Anesthesia for Strategies in Pediatric Anesthesia for the Palm Pilot. Second Edition. Ed.: RS Litman. Pocketmedicine.com, New York, NY, 2007.
  11. Ajuba-Iwuji C and Njoku DB. Rashes. In PocketICUMedicine. Ed: M Wall. Pocketmedicine.com, New York, NY, 2009.
  12. Ajuba-Iwuji C and Njoku DB. Challenges During Surgery for Traumatic Brain Injury. In Essentials of Neuroanesthesia and Critical Care Handbook. Ed: J Kirsch and A Brambrink. Springer, 475, 2012.
  13. Kudchadkar S, Njoku D. Subclavian Steal Syndrome. In: Essence of Anesthesia Practice, M. Roizen and L. Fleisher, editors. New York: W. B. Saunders Company. 309, 2011.
  14. Heitmiller E, Njoku D. Scoliosis in Decision Support in Medicine. 2013
  15. Njoku D, Lyon C Pharmacology: Physiologic States, Pathophysiologic States and Adverse Effects in Essentials of Pediatric Anesthesiology. Cambridge University Press. 2015
  16. Kattail D, Lo C, Njoku D. Orthopedic Surgery in Essentials of Pediatric Anesthesiology. Cambridge University Press. 2015
  17. Geng-Ramos G and Njoku DB. Challenges During Surgery for Traumatic Brain Injury. In Essentials of Neuroanesthesia and Critical Care Handbook. Ed: J Kirsch and A Brambrink. Springer, 2017.
  18. Njoku DB, Chitilian HV and Kronish K. Hepatic Physiology, Pathophysiology and Anesthetic Considerations. in Miller Anesthesia, 9th edition, Elsevier, 2019.
  19. Njoku DB, Drobish J, Chilian HV and Kronish K. Gastrointestinal and Hepatic Physiology, Pathophysiology and Anesthetic Considerations. In Miller Anesthesia, 10th edition, Elsevier, 2024.